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AB Zebrafish Line

University of Oregon Researchers: George Streisinger, Zoltan Varga, Charles Kimmel, Judith Eisen AB Zebrafish Line. Summary of Our Technology: The AB line is derived from two lines, A and B, purchased by Streisinger at different times from a pet shop in Albany, Oregon. The original A and B lines probably originated from a hatchery in Florida. Haploid...

Published: 6/10/2022 | Inventor(s): George Streisinger, Charles Kimmel, Judith Eisen, Zoltan Varga

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Category(s): Veterinary Science, Research Tools

absolute Zebrafish Line

University of Oregon Researchers: David Lains, Zoltan Varga absolute Zebrafish Line. Summary of Our Technology: The absolute line is a cross between two recessive, non-lethal mutations: mitfab692(nacre) and ednrb1ab140 (rose). The result is a transparent zebrafish line that allows observation of organs, as well as fluorescent reporter gene products,...

Published: 6/10/2022 | Inventor(s): David Lains, Zoltan Varga

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Category(s): Agricultural, Research Tools, Veterinary Science

Device and method for creating Gaussian electron beams

University of Oregon Researchers: Benjamin McMorran Patent: 9,240,255 issued 1/19/2016 (UO-13-07) Device and Method for Creating Gaussian Electron Beams. Technology Background/Definition of Problem: Electron beams used in instrumentation such as scanning electron microscopes, transmission electron microscopes, microprobes, etc. exhibit numerous...

Published: 6/10/2022 | Inventor(s): Benjamin McMorran

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Category(s): Engineering, Imaging, Materials Science, Nanoscience & Microtechnologies, Physical Science, Research Tools

Maize Seeds with Mu Insertions

University of Oregon Researchers: Alice Barkan, Rosalind Williams-Carrier, Susan Belcher, Nicholas Stiffler Maize Seeds with Mu Insertions. Description of Innovation: High-copy transposons have been effectively exploited as mutagens in a variety of organisms. However, their utility for phenotype-driven forward genetics has been hampered by the difficulty...

Published: 6/10/2022 | Inventor(s): Alice Barkan, Rosalind Williams-Carrier, Susan Belcher, Nicholas Stiffler

Keywords(s):

Category(s): Agricultural, Research Tools

TARDIS Genetic Data Compression

Technology ID: UO-20-020 Researchers: Zach Stevenson, Stephen Banse, Patrick Philips The TARDIS technology is a high-throughput genetic engineering method for complex multi-cellular organisms. Technology Background: A fundamental tool in molecular biology is the generation of transgenic individuals which have foreign DNA integrated into their...

Published: 3/13/2023 | Inventor(s): Patrick Phillips, Zachary Stevenson, Stephen Banse

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Category(s): Research Tools

Gamma-ketothiocarbamate molecules that release COS

University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...

Published: 5/2/2022 | Inventor(s): Michael Pluth, Yu Zhao

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Category(s): Chemistry, Diagnostics, Engineering, Medical Devices, Physical Science, Research Tools, Therapeutics

Innovative, highly-efficient strategies to purify proteins of interest, determine their genomic binding sites, and target their activity to desired genomic regions

Title: A Unified Strategy to Simplify and Enhance Studies of Protein Function Protein studies are universal across disciplines in biological sciences. Because of this ubiquity, numerous strategies exist to purify, localize, redirect, deplete, and visualize proteins in all model organisms. However, it can be cumbersome to create required strains to...

Published: 5/2/2022 | Inventor(s): Jeff McKnight

Keywords(s): Science

Category(s): Diagnostics, Research Tools

SpdE, a novel amino acid-sensing diguanylate cyclase

SpdE, a novel amino acid-sensing diguanylate cyclase Tech ID UO-19-33 Animals are colonized by dynamic communities of bacteria, largely acquired by transmission from the external environment and other hosts; however, the traits that promote a microbe’s ability to be host-associated (i.e. to colonize or otherwise exist within a host) are not...

Published: 6/21/2024 | Inventor(s): Karen Guillemin, Emily Sweeney, Catherine Robinson

Keywords(s): Science

Category(s): Diagnostics, Research Tools, Therapeutics

Development of a Novel Zebrafish Screening System and Identification of a Novel Protein That Induces Pancreatic Beta-Cell Proliferation

HEADLINE: Novel protein induces pancreatic beta cell proliferation, is ideal for diabetes treatment research Our scientists discovered a novel protein that offers a potential new avenue of research for labs developing drugs to treat diabetes. The newly-discovered BefA (β Cell Expansion Factor A) protein acts to increase total pancreatic...

Published: 10/19/2023 | Inventor(s): Karen Guillemin, Jennifer Hampton

Keywords(s): Biochemistry, Biological Materials, Biotech, Therapeutics, Zebrafish

Category(s): Diagnostics, Therapeutics, Research Tools

Development of a Novel Zebrafish Screening System and Identification of a Novel Protein with Anti-Inflammatory Activity

HEADLINE: Novel protein with strong anti-inflammatory activity has been shown to effectively treat inflammatory bowel disease and prevent septic shock in zebrafish. University of Oregon scientists have discovered a novel protein with strong anti-inflammatory activity. The novel protein has been shown to effectively treat inflammatory bowel...

Published: 11/4/2024 | Inventor(s): Karen Guillemin, Annah Rolig

Keywords(s): Biochemistry, Biological Materials, Biotech, Research Tools, Therapeutics, Zebrafish

Category(s): Research Tools, Therapeutics, Agricultural, Diagnostics

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