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Malassezia-Secreted Factor with Antibiotic Activity

1. Technology Overview The invention introduces a novel antimicrobial activity produced by human-associated fungi, specifically Malassezia sympodialis, for potential development as antibiotics. The secreted factor exhibits bactericidal activity against Staphylococcus aureus and enhances bacterial sensitivity to other antibiotics, making it suitable...

Published: 1/8/2026 | Inventor(s): Matthew Barber, Caitlin Kowalski

Keywords(s):

Category(s): Therapeutics, Diagnostics, Research Tools

AB Zebrafish Line

The AB line is derived from two lines, A and B, purchased by George Streisinger at different times from a pet shop in Albany, Oregon. The original A and B lines probably originated from a hatchery in Florida. Haploid offspring from individual females of the AB line were screened for healthy, good looking embryos, and those females were used to make...

Published: 1/6/2026 | Inventor(s): George Streisinger, Charles Kimmel, Judith Eisen, Zoltan Varga

Keywords(s):

Category(s): Veterinary Science, Research Tools

absolute Zebrafish Line

The absolute zebrafish line is a cross between two recessive, non-lethal mutations: mitfab692(nacre) and ednrb1ab140 (rose). The result is a transparent zebrafish line that allows observation of organs, as well as fluorescent reporter gene products, without invasive manipulations. The double mutant lacks Melanophores (black pigment cells) and iridophores...

Published: 1/6/2026 | Inventor(s): David Lains, Zoltan Varga

Keywords(s):

Category(s): Agricultural, Research Tools, Veterinary Science

Device and Method for Creating Gaussian Electron Beams

University of Oregon Researchers: Benjamin McMorran Patent: 9,240,255 issued 1/19/2016 (UO-13-07) Device and Method for Creating Gaussian Electron Beams. Technology Background/Definition of Problem: Electron beams used in instrumentation such as scanning electron microscopes, transmission electron microscopes, microprobes, etc. exhibit numerous...

Published: 1/8/2026 | Inventor(s): Benjamin McMorran

Keywords(s):

Category(s): Engineering, Imaging, Materials Science, Nanoscience & Microtechnologies, Physical Science, Research Tools

Maize Seeds with Mu Insertions

High-copy transposons have been effectively exploited as mutagens in a variety of organisms. However, their utility for phenotype-driven forward genetics has been hampered by the difficulty of identifying the specific insertions responsible for phenotypes of interest. University of Oregon researchers have invented a new method that can substantially...

Published: 1/6/2026 | Inventor(s): Alice Barkan, Rosalind Williams-Carrier, Susan Belcher, Nicholas Stiffler

Keywords(s):

Category(s): Agricultural, Research Tools

Method for Detection for Hydrosulfide Anion (HS-) and Hydrogen Sulfide (H2S)

1. Technology Overview The invention focuses on a new method for detecting hydrosulfide anion (HS⁻) and hydrogen sulfide (H₂S) using reversible, supramolecular binding interactions. This method utilizes non-covalent interactions, specifically hydrogen bonds, to detect HS⁻/H₂S without altering the analyte concentration. The technology is currently...

Published: 1/7/2026 | Inventor(s): Michael Haley, Darren Johnson, Michael Pluth, Ryan Hansen, Matt Hartle, Blakely Tresca

Keywords(s):

Category(s): Chemistry, Materials Science, Physical Science, Imaging, Therapeutics, Research Tools, Diagnostics

A Unified Strategy to Simplify and Enhance Studies of Protein Function

Protein studies are universal across disciplines in biological sciences. Because of this ubiquity, numerous strategies exist to purify, localize, redirect, deplete, and visualize proteins in all model organisms. However, it can be cumbersome to create required strains to investigate the many different aspects of protein function. Even in yeast, one...

Published: 1/8/2026 | Inventor(s): Jeff McKnight

Keywords(s): Science

Category(s): Diagnostics, Research Tools

SpdE, a Novel Amino Acid-sensing Diguanylate Cyclase

1. Technology Overview The invention introduces SpdE, a novel bacterial protein that senses specific amino acids (valine, proline, and isoleucine) at nanomolar concentrations. This highly sensitive protein offers significant potential for applications in clinical diagnostics, biotechnology, and industrial processes. The technology leverages established...

Published: 1/8/2026 | Inventor(s): Karen Guillemin, Emily Sweeney, Catherine Robinson

Keywords(s): Science

Category(s): Diagnostics, Research Tools, Therapeutics

Development of a Novel Zebrafish Screening System and Identification of a Novel Protein That Induces Pancreatic Beta-Cell Proliferation

This invention enables a novel, microbiome-derived approach to diabetes treatment by leveraging a protein from the gut bacterium Aeromonas that increases pancreatic β cell number through enhanced proliferation, differentiation, and survival. By targeting restoration of insulin-producing β cells, the technology addresses a core unmet need in...

Published: 1/6/2026 | Inventor(s): Karen Guillemin, Jennifer Hampton

Keywords(s): Biochemistry, Biological Materials, Biotech, Therapeutics, Zebrafish

Category(s): Diagnostics, Therapeutics, Research Tools