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Development of a Novel Zebrafish Screening System and Identification of a Novel Protein with Anti-Inflammatory Activity

HEADLINE: Novel protein with strong anti-inflammatory activity has been shown to effectively treat inflammatory bowel disease and prevent septic shock in zebrafish. University of Oregon scientists have discovered a novel protein with strong anti-inflammatory activity. The novel protein has been shown to effectively treat inflammatory bowel...

Published: 5/2/2022 | Inventor(s): Karen Guillemin, Annah Rolig

Keywords(s): Biochemistry, Biological Materials, Biotech, Research Tools, Therapeutics, Zebrafish

Category(s): Research Tools, Therapeutics, Agricultural, Diagnostics

Mutant Fluorescent Proteins (A)

Functional engineered fluorescent proteins with varied fluorescence characteristics that can be easily distinguished from currently existing green and blue fluorescent proteins. Such engineered fluorescent proteins enable the simultaneous measurement of two or more processes within cells and can be used as fluorescence energy donors or...

Published: 1/18/2024 | Inventor(s): Rebekka Wachter, Atsushi Miyawaki, Juan Llopis, Roger Heim, James Remington, Roger Tsien, Andrew Cubitt, Matts Ormo

Keywords(s): Research Tools

Category(s): Research Tools

Monoclonal Antibodies

The University of Oregon's Monoclonal Antibody Facility, in close collaboration with university researchers, developed novel monoclonal antibodies against a variety of proteins and peptides that are used in studies of molecular structure, subcellular activities, and cellular differentiation. Many of these monoclonal antibodies are now available...

Published: 6/10/2022 | Inventor(s):

Keywords(s): Antibodies, Biological Materials, Research Tools

Category(s): Research Tools

TNT, A General Purpose Least Square Refinement for Macro-Molecular X-Ray Crystallography

This package is a complete suite of computer programs for optimizing the fit of macromolecular models to x-ray crystallographic data. The parameters of the atomic model can be restrained to structure factors and the principles of stereochemistry. The programs are very general and can be used for any macromolecular problem. A model can be restrained...

Published: 8/3/2022 | Inventor(s): Dale Tronrud

Keywords(s): Research Tools, Software

Category(s): Software, Imaging, Materials Science